2018-02-12T10:35:28.000Z2025-05-12 04:35:20
locus
BSU24770
BSU_24770
geneLength
378
381
outlinks
bsu
BSU24770
BSU_24770
Gene
Coordinates
2,564,026 → 2,564,406
2,564,026 2,564,406
The protein
Protein family
arsC family (according to Swiss-Prot) Arsenate Reductase (ArsC) family, Spx subfamily
ArsC family (with [[protein|Spx]] and [[protein|YusI]], according to UniProt)
The protein
Paralogous protein(s)
[[protein|Spx]]
[[this]]
The protein
Modification
[[protein|MgsR]] is subject to post-translational redox-sensitive activation by intramolecular disulfide bond formation in response to ethanol stress [Pubmed|22812682]
[[protein|MgsR]] is subject to post-translational redox-sensitive activation by intramolecular disulfide bond formation in response to ethanol stress [Pubmed|22812682]
phosphorylation on R17, R95 by [[protein|McsB]], this tags the protein for degradation by [[protein|ClpX]]-[[protein|ClpP]] [pubmed|32477307,30962353]
Biological materials
Mutant
MGNA-C476 (yqgZ::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2474 NBRP B. subtilis, Japan]
BKE24770 (Δ[[gene|mgsR]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE24770 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTCGTTTTTTCCTCCTCA, downstream forward: _UP4_TGATGAAAAACCGAAGATCC
BKK24770 (Δ[[gene|mgsR]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK24770 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTCGTTTTTTCCTCCTCA, downstream forward: _UP4_TGATGAAAAACCGAAGATCC
MGNA-C476 (yqgZ::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2474 NBRP B. subtilis, Japan]
BKE24770 ([[gene|mgsR]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE24770 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTCGTTTTTTCCTCCTCA, downstream forward: _UP4_TGATGAAAAACCGAAGATCC
BKK24770 ([[gene|mgsR]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK24770 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTCGTTTTTTCCTCCTCA, downstream forward: _UP4_TGATGAAAAACCGAAGATCC
References
Expression and Regulation
additional information
half-life of the protein: 6 minutes [pubmed|32477307]